| Company | Year established locally | Employees | Local offices/locations | Type of business | Top executive | |
| 1 | MGM Resorts International 3600 Las Vegas Blvd. South Las Vegas, NV 89109 702-693-7111 • mgmresorts.com |
2000* | 62,000 | 14 | Entertainment and hospitality | James Murren, chairman, CEO |
| 2 | Caesars Entertainment Corp. 1 Caesars Place Drive Las Vegas, NV 89109 702-407-6000 • caesars.com |
1966 | 24,000 | 12 | Resort operator | Mark Frissora, president, CEO |
| 3a | Station Casinos 1505 S. Pavilion Center Drive Las Vegas, NV 89135 702-495-3000 • sclv.com |
1976 | 12,000 | 20 | Entertainment, gaming, hospitality | Frank J. Fertitta III, chairman, CEO |
| 3b | Wynn 3131 Las Vegas Blvd. South Las Vegas, NV 89109 702-770-7000 • wynnlasvegas.com |
2005 | 12,000 | 2 | Resort/casino | Steve Wynn, chairman, CEO |
| 5 | Boyd Gaming Corp. 6465 S. Rainbow Blvd. Las Vegas, NV 89118 702-792-7200 • boydgaming.com |
1975 | 9,300 | 11 | Casino entertainment | Keith Smith, president, CEO |
| 6 | Las Vegas Sands Corp. 3355 Las Vegas Blvd. South Las Vegas, NV 89109 702-414-1000 • sands.com |
1990 | 9,088 | 1 | Resort operator | Sheldon Adelson, chairman, CEO |
| 7 | The Valley Health System 10105 Banburry Cross Las Vegas, NV 89144 valleyhealthsystemlv.com |
1972 | 6,500 | 7 | Health care/hospitals | Karla Perez, regional vice president |
| 8 | McDonald’s Greater Las Vegas Operator Association 2217 N.Green Valley Parkway Henderson, NV 89014 702-454-3485 • mcdonalds.com |
1966 | 5,040 | 100+ | Fast food | James Vance, president |
| 9 | The Cosmopolitan 3708 Las Vegas Blvd. South Las Vegas, NV 89109 702-698-7000 • cosmopolitanlasvegas.com |
2010 | 5,000 | 1 | Resort operator | William McBeath, president, CEO |
| 10 | UnitedHealthcare/Southwest Medical Associates 2724 N. Tenaya Way Las Vegas, NV 89128 702-242-7000 • uhcnevada.com |
1980 | 4,273 | 46 | Health care provider/insurance provider | Don Giancursio, CEO of UnitedHealthcare; Dr. Robert McBeath, president, CEO of SMA |
* The company began operations in 1986 as MGM Grand Inc.
Source: VEGAS INC research. It is not the intent of this list to endorse the participants or to imply that the listing of a company indicates its quality. Although every attempt is made to ensure the accuracy and thoroughness of VEGAS INC charts, omissions sometimes occur and some businesses do not respond. Please send corrections or additions on company letterhead to Julie Ann Formoso, research associate, VEGAS INC, 2275 Corporate Circle, Suite 300, Henderson, NV 89074.